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            The Sanders Lab aims to identify the etiology of developmental disorders through the discovery of genetic risk factors. Over the past few years there has been rapid progress in identifying the genes that play a role in autism spectrum disorder (ASD). We aim to continue this progress, leverage these findings to build a more complete understanding of ASD, and to extend this approach to other human disorders, including congenital malformations.

            There are five main areas of research:

            1. Gene discovery: Genomic analysis of DNA using high-throughput sequencing to identify genes associated with human disorders
            2. Understanding the noncoding genome: Using whole-genome sequencing to identify the elements of the noncoding genome that contribute to ASD
            3. The role of SCN2A in human disorders: SCN2A mutations are one of the most common causes of ASD; we aim to understand how this risk is mediated with the view to developing therapeutics
            4. Understanding neurodevelopment: Leveraging functional genomic data to understand physiological brain development and the pathology associated with neuropsychiatric disorders
            5. Sex bias in ASD: Identifying genes and gene networks that lead to the preponderance of males diagnosed with ASD

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            The Sanders Lab is primarily a bioinformatic group that uses a wide range of genomic, bioinformatic, and statistical methods including: whole-exome sequencing, whole-genome sequencing, de novo mutation detection, RNA-Seq, and ChIP-Seq.

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            We work with closely with numerous collaborators, including the State Lab and Bender Lab at UCSF, the Devlin Lab at UPMC, the Roeder Lab at Carnegie Mellon, the Sestan Lab, and the Talkowski lab at Harvard.

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            If you are interested in joining please go to the recruitment page.

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            We are grateful for funding from the National Institute of Mental Health and the The Simons Foundation Autism Research Initiative, the Autism Science Foundation, and the 基于golang实现代理IP抓取实例_Man_ge的博客-CSDN博客:2021-6-10 · 直接上code/* golang 的代理ip采集*/package mainimport ( fmt math/rand time strings regexp database/sql Man-Li CSDN 认证博客专家 CSDN认证企业博客 ....

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            Dec 13th 2018

            New paper! An et al. 2018 published in Science, highlights the role of promoters in autism.

            Dec 1st 2018

            Our work with the Autism Sequencing Consortium identifies 99 autism genes, paper submitted to 代理ip大全.

            May 29th 2018

            Donna presents the lab’s recent work, 虚拟ip地址代理软件_优惠券-抓券网:2021最新_虚拟ip地址代理软件_优惠券免费领取-抓券网 独家内部优惠券直播!每天万款内部优惠券免费领取、让您享受更多优惠! at the PGC Statistical Genetics Group online meeting.

            May 9th 2018

            Stephan, Donna, Brooke and Joon travel to Rotterdam, Netherlands, to share our latest work at INSAR 2018.

            May 7th 2018

            Donna and Joon’s latest works highlighted in Autism Science Foundation Podcast.

            April 27th 2018

            New paper! 免费高匿代理ip地址 published in Nature Genetics in collaboration with the Autism Sequencing Consortium.

            April 12th 2017

            Stephan with Kevin Bender (UCSF) talk about 'The genetics and physiology of SCN2A in autism and early-onset seizures' at the Simons VIP Connect.

            Nov 30th 2016

            Donna talks about 'The Role of Sex-Differential Biology in Risk for Autism Spectrum Disorder' at the SFARI Webinar Series.

            April 21th 2016

            Stephan talks about 'The Genetics of Autism' at the University of California Television.

            ... see all News

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